Q: What did the Dalmatian say after eating lunch?
A: Wow, that really hit the spot!
Explanation: If you have seen the movie 101 Dalmatians, you know that Dalmatians are a breed of dog known for their spots. While I like dogs, having 101 of them seems like a lot!
That hit the spot is an idiom meaning something that was needed. In this joke the speaker, the Dalmatian, was hungry and lunch hit the spot: lunch is exactly what was needed.
This joke is funny because it plays with the idea of hitting the spot (the markings on a Dalmatian) and hitting the spot (being exactly what was needed).
If you want to learn more about Dalmatians, this will hit the spot: